The EGEA cohort

Epidemiological study of genetic factors
and environmental factors of asthma,
hyperreactivity bronchial and atopy.

The latest results

Thanks to the follow-up of the EGEA population, which enabled repeated assessment of cleaning product exposure and respiratory health, a recent study suggests that long-term weekly use of spray cleaning products may have a negative effect on the evolution of asthma symptoms.

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Pacheco Da Silva E* et al. - Longitudinal associations of household use of cleaning agents and asthma symptoms in women: the EGEA study - Occup Environ Med. 2023 Apr

A recent study based on two French cohorts (CONSTANCES and EGEA) shows that allergic rhinitis and non-allergic rhinitis, alone or associated with asthma and conjunctivitis, are quite distinct phenotypes. Results indicate that participants with asthma and conjunctivitis had more severe rhinitis.

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Savouré M et al. - Rhinitis phenotypes and multimorbidities in the general population Constances cohort - Eur Respir J. 2023 Feb 9

Few studies have examined the association between exposure to indoor moulds and rhinitis in adults. In the EGEA study, we showed that exposure to indoor moulds was associated with current and allergic rhinitis, suggesting the need for preventive measures against indoor mould growth.

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Orsi L et al. - Indoor visible moulds and rhinitis in adults: The EGEA study - Allergy. 2022 Sep 22.doi: 10.1111/all.15525. Online ahead of print.

News

New EGEA4 follow-up

05/09/2023

The new cohort follow-up, EGEA4, has begun! The study is being launched in several stages. Participants at the Grenoble center…

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EGEA annual seminar 2023

05/09/2023

The EGEA cohort's annual seminar took place on June 1-2, 2023 in Bivier, near Grenoble. Each year, this meeting provides…

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2120

participants in total since the beginning of EGEA (2047 EGEA1 / 1601 EGEA2 / 1557 EGEA3)

phases of the study

years of follow-up

66000

tubes of biological samples stored

> 150

scientific publications

> 200

scientific communications at international conferences

The EGEA cohort

in a few words

The epidemiological EGEA cohort (Epidemiological study on the Genetics and Environment of Asthma, bronchial hyperresponsiveness and atopy) was initiated in 1991 to meet the following general objectives:

to identify the genetic factors of asthma
to identify the environmental factors of asthma
to clarify the clinical heterogeneity of asthma.

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Who participates in the study?

In the first phase of the EGEA study (EGEA1), 388 asthma families and 415 participants from the general population were included, representing 2047 participants with or without asthma.
During the second phase of the study, 73 new family members joined the study. A total of 2120 participants participated in at least one phase of the study…

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